HELLENIC ASSOCIATION DERMATOLOGY - VENEREOLOGY
CAT SCRATCH DISEASE
AIDS Patients at Risk From Germs in Cats and Lice" Washington Times (12/25/97) P. A7 An Ulcerated Nodule Associated With Lymphadenopathy. Diagnosis: Cat-scratch disease (CSD). Arc Dermatol Angiomatosis bacilar Miguel R. Sánchez, M.D. & Zoila del Rocío Flashner, M.D. Angiomatosis, and Related Syndromes Marra CM. Neurologic complications of Bartonella henselae infection. Department of Medicine, University of Washington School of Medicine, Seattle, USA. Curr Opin Neurol 1995 Jun;8(3):164-9 Atypical Cat-scratch Disease Archives of Pediatrics & Adolescent Medicine / volume:153 (page: 761) Azithromycin and Cat-scratch Disease. Benjamin Estrada, MD, University of South Alabama. [Infect Med 15(8):517, 1998. ``Although cat-scratch disease (CSD) was first described in 1950, significant progress on elucidating its pathogenesis, creating safe and accurate diagnostic tests, and defining effective treatment were not achieved until this decade. Bartonella(formerly Rochalimaea) henselae was identified as the etiologic agent of CSD in1992 (Regnery RL, et al: Lancet 1992; 339:1443-1445). The same organism wasfound to be the cause of bacillary angiomatosis, which usually affectsimmunocompromised individuals. Medscape. Azithromycin for Bacillary Angiomatosis. Guerra LG, Neira CJ, Boman D et al. Rapid Response of AIDS-Related Bacillary Angiomatosis to Azithromycin. Clin Infect Dis 17(8):264-6, August 1993. February 1994, Volume 3, No. 2. Bacillary angiomatosis Bacillary Angiomatosis Bacillary angiomatosis Bacillary Angiomatosis - A Recently Described Infectious Disease Bacillary angiomatosis: A unique cutaneouscomplication of HIV infection. Joan Lipa MD, Walter Peters PhD MD FRCSC, Victor Fornasier MD FRCPC, Benjamin Fisher MD FRCPC. Divisions of Plastic Surgery, Pathology and Dermatology, Wellesley Hospital, University of Toronto, Toronto, Ontario. Bacillary Angiomatosis - A Short Review by Margot Whitfeld (NSW) Bacillary angiomatosis (Bartonella ) nodules Bacillary angiomatosis (Bartonella ) biopsy slide The AIDS Knowledge Base" Bacillary Angiomatosis . LGVMA's GOOD NEWS! Bacillary Angiomatosis. Radiology 1995; 197: 67-72 Bacillary Angiomatosis Authored by Peter Angritt, M.D., Bacillary Angiomatosis, buccal mucosa (notice the similarity in appearance to Kaposi's sarcoma) John Valentine. Bacillary angiomatosis in an immunocompetent child: The first reported case Paul MA, Fleischer JAB, Wieselthier JS, et al Source: Pediatr Dermatol 1994;11:338-341. "The AIDS Knowledge Base" Bartonella !Bartonella is what we know! Bartonella henselae Bartonella henselae (formerly Rochalimaea henselae) is a small gram-negative rod, that has recently been identified as the causative agent of Cat Scratch Disease in humans. The organism is zoonotic with the domestic cat as its reservoir.... LGVMA's GOOD NEWS! BARTONELLA IFA IgG Bartonella Infections:Diverse and Elusive JEFFERY S. LOUTIT Stanford University Bartonella Presentation Bartonella spp. Terence Joe. Fuller Laboratories Bartonella-Associated Infections in HIV-Infected Patients Koehler, Jane E. AIDS Clinical Care (12/95) Vol. 7, No. 12, P. 97 BARTONELLA (CAT SCRATCH DISEASE - CSD) Bartonella: Bacillary Angiomatosis and Bacillary Peliosis Agents. This chapter is modified with permission of JE Koehler and the University of Chicago Press from AIDS commentary-bacillary angiomatosis and bacillary peliosis in patients infected with human immunodeficiency virus. Clin Infect Dis 1993;17:612-624. Bites Animal Cat Scratch 1999, Scott Moses, MD Cat Owners Run High Risk of Bartonella Infection By: Todd Zwillich, Staff Writer [Skin & Allergy News 28(12):9, 1997 Medscape Cat Scratch Cat Scratch (Bartonella henselae) Endophthalmitis Author: C. Diane Song, MD Cat scratch disease Cat Scratch Disease Cat Scratch Disease Cat Scratch Disease Bug Bytes Volume 1 Number 1 Cat Scratch Disease Cat Scratch Disease Cat Scratch Disease - Overview Cat Scratch Disease ``Cat scratch disease (CSD), is the most common cause of chronic, benign adenopathy in children and young adults. Each year almost 24,000 Americans, 80% of whom are immunocompetent and younger than 21 years of age, acquire CSD. The diagnosis of CSD is clinical and requires three of the following: a scratch, bite, or primary lesion caused by a cat; a positive skin test; otherwise unexplained lymphadenopathy; or characteristic histopathology of a node biopsy.`` LSU Medical Center Cat Scratch Disease and Associated Syndromes Antibody Profile (163162) Laboratory Corporation of America Cat-scratch disease and bacillary angiomatosis B.B. CHOMEL. Rev. sci. tech. Off. int. Epiz., 1996, 15 (3), 1061-1074 Cat scratch disease bacteria may be transmitted to cats by fleasWhile a cat scratch may be the most common vehicle for transmitting CSD to people, the common cat flea is probably the vector for cats. Infectious Disease News Cat scratch disease bacteria may be transmitted to cats by fleasWhile a cat scratch may be the most common vehicle for transmitting CSD to people, the common cat flea is probably the vector for cats. Infectious Disease News Cat Scratch Disease in Humans By Dr. Margaret Muns, DVM Cat Scratch Disease KidsHealth.org Cat scratch disease MAYO CLINIC Cat Scratch Disease MM Carr DDS MD MEd CAT SCRATCH DISEASE TRANSMITTED BY FLEAS American Society for Microbiology CAT SCRATCH DISEASE Vanderbilt University Medical Center CAT SCRATCH DISEASE [Cat Scratch Fever, Benign Lymphoreticulosis, Benign nonbacterial Lymphadenitis, Bacillary Angiomatosis, Bacillary Peliosis Hepatis] Kansas State University. CAT SCRATCH DISEASE ``Classical cat scratch disease (CSD) is considered a relatively benign, self-limiting disease in people. Frequently, an inoculation papule, which can persist for months, is located at the site of a bite or scratch. Intermittent fever, lymphadenopathy and lethargy may be the only clinical manifestations of CSD. Approximately 10% of currently recognized CSD cases are accompanied by atypical manifestations, including tonsillitis, encephalitis, endocarditis, cerebral arteriosis, transverse myelitis, granulomatous hepatitis and/or splenitis, osteolysis, pneumonia, pleural effusion, and thrombocytopenic purura.`` North Carolina College of Veterinary Medicine Cat Scratch Disease by Susan Little, DVM CFA Health Committee Cat Scratch Disease Cat scratch disease (CSD), is the most common cause of chronic, benign adenopathy in children and young adults. Each year almost 24,000 Americans, 80% of whom are immunocompetent and younger than 21 years of age, acquire CSD. The diagnosis of CSD is clinical and requires three of the following: a scratch, bite, or primary lesion caused by a cat; a positive skin test; otherwise unexplained lymphadenopathy; or characteristic histopathology of a node biopsy. Cat Scratch Disease Children's Health Cat Scratch Disease Colorado State University Office of Biosafety; June 16, 1998. Cat Scratch Disease Excite Inc. Cat Scratch Disease UC - University of the Carolinas Cat Scratch Disease CAT SCRATCH DISEASE Mitch Brock, MD. BCOM Otolaryngology Cat Scratch Disease. Answered by Robert Steele, MD. ParentsPlace.com Cat scratch disease: The story continues. MA OPAVSKY Can J Infect Dis 1997;8(1):43-49. Cat Scratch Disease-Synonyms: Cat Scratch Fever. Authored by Joyce R. Drayton, M.D. , Assistant Professor of Medicine, Division of Infectious Disease, Morehouse School of Medicine. emedicine.com Cats Implicated in Bacterial Threat to PWAs. From Alive and Kicking!'s FASTFAX #157 December 28, 1997 CAT-SCRATCH DISEASE Cat-Scratch Disease Cat-Scratch Disease - Cat-scratch disease is an uncommon illness that can be transmitted to people by pet cats. The agent that causes cat-scratch disease is a rickettsial (bacteria-like) organism called Bartonella henselae. Cat-Scratch Disease associated with Neuroretinitis M. PHOTOPOULOU, ART. EXARCHOU, P. PAIKOS Ophthalmological Dept. of “Ag. Sophia” Childrens' Hospital Cat-Scratch Disease ASTDHPPHE Cat-Scratch Disease by Charles H. Booras, MD. 5/3/97 ``Cat-scratch disease is an infection caused by bacteria (germs) carried in cat saliva. The bacteria can be passed from a cat to a human. Cats may get the bacteria from ticks and fleas, although this hasn't been clearly proven yet. Studies in the early 1990's found that the Bartonella henselae bacterium is responsible for the disease. Approximately 38% of household cats tested positive for the bacterium in one study from 1992. Cat-Scratch Disease DrugBase Cat-Scratch Disease. from Your Family Doctor Cat-Scratch Disease ``Cat-scratch disease is an infection caused by bacteria (germs) carried in cat saliva. The bacteria can be passed from a cat to a human. Cats may get the bacteria from ticks and fleas, although this hasn't been clearly proven yet. Studies in the early 1990's found that the Bartonella henselae bacterium is responsible for the disease. Approximately 38% of household cats tested positive for the bacterium in one study from 1992. by Charles H. Booras, MD 5/3/97 Cat scratch disease. Histology image. 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medical Sciences, Budapest, Hungary Pathology Pathway Cat Scratch Disease. Dr. Robert P. Ellis Cat-Scratch Disease By Physicians of the Penn State Geisinger Health System Cat Scratch Disease Authored by Joe Lex, M.D., Department of Emergency Medicine, Chestnut Hill Hospital Joe Lex, M.D. is a member of the following medical societies: American Academy of Emergency Medicine, and American College of Emergency Physicians. Edited by Jeffrey Glenn Bowman, M.D., M.S., Department of Emergency Medicine, Mercy Springfield Hospital;
Francisco Talavera, Pharm.D., Ph.D., Department of Pharm
Cat-Scratch Disease and Related Clinical Syndromes DAVID L. SMITH, M.D. West Jersey Family Practice Residency, Voorhees, New Jersey. American Family Physician April 1997 Cat-Scratch Disease: Etiology, Diagnosis, and Therapy Cat-Scratch Disease: An Update of the Case for a Rochalimaea Etiology Author: Russell L. Regnery, PhD, Centers for Disease Control and Prevention. Medscape. Cat scratch disease: Diagnosis and management Infectious Diseases and Immunization Committee, Canadian Paediatric Society (CPS) Approved by the CPS Board of Directors in 1996 Paediatrics & Child Health 1997;2(4):275-8 Cat-Scratch Disease: Etiology, Diagnosis, and Therapy Author: Andrew M. Margileth, MD, University of Virginia Health Sciences Center, Charlottesville. Medscape Cat-Scratch Disease AAFP CAT-SCRATCH FEVER HealthGate CAT-SCRATCH FEVER Cat-scratch fever is a disease caused by a bacteria, as yet unnamed, that is transmitted by the scratch or bite of a healthy cat. It develops 7 to 14 days after the scratch or bite. Inflammation of the affected area heals in a few days, but lymph nodes in the area remain slightly swollen and tender. A mild fever and general feeling of being unwell may persist from two weeks to a month. The World Book Rush-Presbyterian St. Luke's Medical Center Medical Encyclopedia. CAT-SCRATCH FEVER OVERVIEW. Dr. Chamberlain, Cat Scratch (Bartonella henselae) Endophthalmitis CHARACTERIZATION OF BARTONELLA HENSELAE PROTEINS BY ELECTROPHORESIS IN SDS-POLYACRYLAMIDE GEL AND WESTERN BLOTTING Sudhir B. Consider Cat Scratch Disease in Child With Unexplained Fever By: Miriam E. Tucker, Senior Writer. [Pediatric News 32(3):16, 1998. Medscape Cutaneous Bacillary Angiomatosis CYTOPATHNET SM Image Database. Histology image Dermatologic Manifestations of HIV Infection HIVINSITE Diagnosis and Management of Cat-Scratch Disease in Primary Care. Nancy H. Busen, PhD, RN, CS Doctors' Answers to "Frequently Asked Questions" - Cat Scratch Fever DRUG INFONET Epidemiologic Notes and Reports Encephalitis Associated with Cat Scratch Disease -- Broward and Epidemiology of Bartonella Infections with Bacillary Angiomatosis by Richard Allen Johnson, MD. Beth Israel-Deaconess Medical Center, Harvard Medical School. Skindex Epidemiology of Bartonella Infections with Bacillary Angiomatosis.by Richard Allen Johnson, MD. Beth Israel-Deaconess Medical Center, Harvard Medical School. Skindex Figure 1 (69K microscopic) Figure 2 (69K microscopic) Figure 3 (75K microscopic) Figure 4 (59K microscopic) Figure 2. Bacillary angiomatosis (Bartonella ) nodules Fine Needle Aspiration Diagnosis of Intramuscular Bacillary Angiomatosis A Case Report Authors: Miguel A. Sanchez, M.D., and Edwarda Rorat, M.D. Health Care For Feral Cats Heska Obtains Exclusive License for Cat Scratch Disease Vaccine Technologies AEGIS. How can cat scratch disease be prevented? National AIDS Treatment Information Project How is cat scratch disease diagnosed? National AIDS Treatment Information Project How is it treated?National AIDS Treatment Information Project Image of the Month Answer Infection with Bartonella (rochalimaea) UPHS/IDSA Guidelines Infections Due to Bartonella: Bacillary Angiomatosis HIVINSIT Interaction of Bartonellahenselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasomeChristoph Dehio, Marlene Meyer, Jürgen Berger, Heinz Schwarz and Christa Lanz. Max-Planck-Institut für Biologie, Abteilung Infektionsbiologie, Spemannstraße 34, D-72076 Tübingen, Germany. The Company of Biologists Ltd. 1999. Les bartonelloses : II. Autres Bartonella responsables de maladies humaines Molecular Epidemiology of Bartonella Infections in Patients with Bacillary Angiomatosis-Peliosis.Jane E. Koehler, Melissa A. Sanchez, Claudia S. Garrido, Margot J. Whitfeld, Frederick M. Chen, Timothy G. Berger, Maria C. Rodriguez-Barradas, Philip E. LeBoit, Jordan W. Tappero. The New England Journal of Medicine -- December 25, 1997 -- Vol. 337, No. 26 Neurologic complications of Bartonella henselae infection. Curr Opin Neurol. 1995 Jun;8(3):164-9. Unique Identifier : AIDSLINE MED/96023831 Marra CM; Department of Medicine, University of Washington School of; Medicine, Seattle, USA. NORD - Cat Scratch Disease Palm Beach Counties, Florida, 1994 MMWR 43(49);909,915-916 Pediatric notes Persistent Infection of Pets within a Household with Three Bartonella SpeciesDorsey L. Kordick, Edward B. Breitschwerdt, North Carolina State University, Raleigh, North Carolina, USA. Emerging Infectious Diseases. Medscape Prevalence of Bartonella species in domestic cats in The Netherlands. Bergmans-AM; de-Jong-CM; van-Amerongen-G; Schot-CS; Schouls-LM . J-Clin-Microbiol. 1997 Sep; 35(9): 2256-61. PRIMÄRE MANIFESTATIONEN VON BARTONELLA HENSELAE-INFEKTIONEN IM KOPF-HALS-BEREICH – EINE PROSPEKTIVE STUDIE GJ. Ridder, B. Richter, R. Laszig, A. Sander Prevention of disease UPHS/IDSA Guidelines Prevention of exposure UPHS/IDSA Guidelines Prevention of recurrence UPHS/IDSA Guidelines Rochalimaea Rochalimaea: Bacillary Angiomatosis and Bacillary Peliosis Agents. Strategy to detect and identify Bartonella species in routine clinical laboratory yields Bartonella henselae from human immunodeficiency virus-positive patient and unique Bartonella strain from his cat. J Clin Microbiol. 1995 Aug;33(8):2107-13. Unique Identifier : AIDSLINE MED/96057595 Clarridge JE 3rd; Raich TJ; Pirwani D; Simon B; Tsai L; Rodriguez-Barradas MC; Regnery R; Zollo A; Jones DC; Rambo C; Laboratory Service, Veterans Affairs Medical Center, Houston,; Texas, USA. Suppurative granuloma - Cat Scratch disease The organism causing bacillary angiomatosis also causes an infectious lymphadenopathy. What is the organism? What is the infectious lymphadenopathy? `` The etiologic agent for bacillary angiomatosis is Bartonella (formerly Rochalimaea) henselae. Bacillary angiomatosis usually affects immunocompromised individuals. The organism is also the cause of the infectious lymphadenopathy cat-scratch disease.``Source: Estrada B: Pediatric Bulletin: Azithromycin and Cat-scratch Disease. Infect Med 15(8):517, 1998. Medscape Thoracic manifestations of Bacillary Angiomatosis In Aids. EH Moore, LA Russell, and JS Klein (Univ. of California, Davis Medical Center, Sacramento, CA 95817 and Barrows Neurological Institute, Phoenix, AZ) Unraveling Mysteries Associated with Cat-Scratch Disease, Bacillary Angiomatosis, and Related Syndromes Authors: Russell Regnery, PhD, Jordan Tappero, MD, National Center for Infectious Diseases, Centers for Disease Control and Prevention. Medscape USPHS 1995 Guideline: Infection with Bartonella (FormerlyRochalimaea) What are its symptoms and signs? National AIDS Treatment Information Project What are the signs of cat-scratch disease? AAFP What is "cat-scratch fever," and why do children get it? November 10, 1997. Alan Greene, M.D., F.A.A.P. What is cat scratch disease?National AIDS Treatment Information Project What is the most common cause of chronic adenitis, persisting longer than 21 days, in children, and how is the diagnosis made?``Cat Scratch Disease (CSD) is the most common cause of pediatric chronic adenitis. Caused by Bartonella henselae, also the etiologic agent of bacillary angiomatosis, CSD is usually a benign self-limited syndrome characterized by the appearance of a papule or pustule at the site of a cat scratch or bite, three to ten days after inoculation, followed two to three weeks later by regional lymphadenopathy with fever. The regional lymph node may be severely enlarged (>3 cm) and tender, and may persist for several weeks to months. Single node adenopathy occurs in half of patients, and multiple-site involvement in one third. Atypical manifestations of CSD are rare, and include encephalitis, radiculitis, and neuroretinitis.`` Source: Alvarado, FS, Dalovisio, JR and Hoadley, DJ: A young woman with sudden visual loss. Infect Med 13 (12): 1009-1010, 1013, 1045. 1996. Medscape What is the relationship between cat scratch disease and HIV disease? National AIDS Treatment Information Project Which antimicrobial(s) should be used as first-line therapy for cat-scratch disease? Medscape Zoonoses: cats, fleas, and bacteria Reprinted from the April 1994 issue of Medical Sciences Bulletin , published by Pharmaceutical Information Associates, Ltd.
G. Karakatsanis, Dermatologist.